When Henry Foots sought Dr. Now's help, he was 47 years old and weighed 715 pounds, the heaviest patient in Season 1. The first season of "My 600-lb Life" chronicled seven years (2004-2011) in four patients' lives, unlike later seasons that featured only the first year of multiple patients' journeys. For Foots, his weight-loss story featured several major obstacles along the way, including flatlining during surgery before being resuscitated. The horrific experience left Foots shaken but more determined than ever to reclaim his life. By the end of his episode, Foots revealed a remarkable weight loss of 440 pounds (via Starcasm).

Freed from the constraints of his weight, Foots returned to work as a shuttle bus driver in 2012. A few months later, Foots experienced what police called a "medical episode" that resulted in him losing control of his bus, which then struck and killed a 43-year-old woman (via Click2Houston). Then, in May 2013, Foots died. The exact cause of death remains unknown, though reports state that his death was not related to his weight or the bus accident in 2012. Henry Foots was the first "My 600-lb Life" alum to die. Since his passing, seven other featured patients have died.